Non-Hodgkin lymphoma (Cancer Book 14)

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The type of staging that BC Cancer uses is based on the Ann Arbor classification, plus we consider the size of the individual tumour s.


  1. Cancer types?
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All Rights Reserved. David Huntsman named Aubrey J. Tingle Prize recipient Moving on up — new exercise resources for cancer patients Dr. This information should not be used for self-diagnosis or in place of a qualified physician's care. The basics. These cancers are also called NHL or malignant lymphoma, or lymphoid cancers. Thomas Hodgkin first described lymphoma in the s.

Non-Hodgkin Lymphoma

There are many types of lymphoma with different names. Waldenstrom's Macroglobulemia, lymphomatoid granulomatosis, lymphomatoid papulosis, and MALT are all types of lymphoma. Most other types have "lymphoma" in the name. Lymphomas are cancers that arise from lymphocytes, which are white blood cells that circulate primarily through the lymphoid system.

The lymphoid or lymphatic system is part of the immune system, which protects against infection. The lymphoid system consists of: lymph nodes, lymphatic vessels, lymph fluid and lymph tissue in other organs such as the spleen, thymus, bone marrow. Lymphatic vessels are a network to carry lymph fluid between the nodes and through the body. Non-Hodgkin lymphomas are called B-cell or T-cell lymphoma depending on the type of lymphocyte that has become cancerous.

B-cell lymphocytes come from the bone marrow. T-cell lymphocytes come from the thymus, a gland in the central part of the chest. T-cell lymphomas are less common and have a greater chance of recurring. The gastrointestinal tract GI is a common site, as are the liver, spleen or bone marrow. Lymphomas can involve the coverings of the brain the meninges and the fluid surrounding the brain cerebrospinal fluid or CSF.

The eyes, testicles or sinuses are other areas of the body where lymphoma may grow. What causes it and who gets it? Previous exposure to radiation or chemotherapy can make people vulnerable to lymphoma. Exposure to some chemicals, including herbicides, may increase risk. People who take drugs that suppress the immune system have a higher risk of lymphoma, e. Some diseases or infections are risk factors; eg. Risk increases with age.

Researchers are looking at other possible risk factors, such as obesity, autoimmune diseases, or familial factors. Changes in research and treatments for lymphoma are ongoing and frequent.

Non-Hodgkin Lymphoma

Since the causes are not understood, there is no known way of preventing this disease. Signs and symptoms Most symptoms of lymphoma are also found in other less serious disorders. These symptoms are usually caused by something else, and are not likely to be a sign of lymphoma. However, it is always important to have symptoms checked by a health professional. Painless enlarged lymph nodes in neck, groin or armpit Fatigue Shortness of breath Itchiness on the trunk of the body Unusual back or abdominal pain Abdominal swelling The following are called "B symptoms" and they are important in planning treatments:.

Persistent fever whose cause is unknown Unexplained night sweats, sometimes so much that the bed sheets have to be changed Unexplained weight loss. An accurate diagnosis in lymphoma is very important since specific types of lymphoma respond to very different forms of treatment, making them different from other cancers. A very thorough medical and physical examination will be done, with attention to lymph nodes, spleen, liver and pain in bones.

Blood and urine samples will be taken for laboratory testing, including a complete blood count, blood chemistry tests, and cell and tissue analyses. A chest X-ray will be taken. A surgical biopsy removes the affected lymph node s or other tissue, and specialists will look at the cells under a microscope to find out what kind of lymphoma it is, and where it is located. Additional tests are sometimes done, such as: Imaging scans of bones or organs such as the liver and spleen Gastrointestinal tests including endoscopy, which is using a scope to view the stomach and intestines Spinal tap lumbar puncture to examine the cerebrospinal fluid CSF.

April Archived from the original on 6 July World Health Organization. Chapter 2. June 1, Archived from the original on 12 August Cancer Research UK. Archived from the original on 14 August Conn's Current Therapy Elsevier Health Sciences. Archived from the original on Japanese Journal of Radiology. Epidemiology, molecular signature and clinical management".


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Archived PDF from the original on HIV Therapy. Retrieved Dec 15, Cancer in Adolescents and Young Adults. Springer, , p. Archived from the original on 7 October Retrieved 28 October Diffuse large B-cell lymphoma Intravascular large B-cell lymphoma Primary cutaneous marginal zone lymphoma Primary cutaneous immunocytoma Plasmacytoma Plasmacytosis Primary cutaneous follicle center lymphoma.

Hepatosplenic Angioimmunoblastic Enteropathy-associated T-cell lymphoma Peripheral T-cell lymphoma not otherwise specified Lennert lymphoma Subcutaneous T-cell lymphoma. Acute biphenotypic leukaemia. Lymphoproliferative disorders X-linked lymphoproliferative disease Autoimmune lymphoproliferative syndrome Leukemoid reaction Diffuse infiltrative lymphocytosis syndrome.

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Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns with nodular pattern Jessner lymphocytic infiltrate of the skin. Namespaces Article Talk.

Views Read Edit View history. In other projects Wikimedia Commons. By using this site, you agree to the Terms of Use and Privacy Policy. Micrograph of mantle cell lymphoma , a type of non-Hodgkin lymphoma. Hematology and oncology. Enlarged lymph nodes , fever , night sweats , weight loss , tiredness , itching [1]. Poor immune function , autoimmune diseases , Helicobacter pylori infection , hepatitis C , obesity , Epstein-Barr virus infection [1] [3]. Bone marrow or lymph node biopsy [1].

Introduction

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